Assay Detail
Binding
CHEMBL648166
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Inhibitory activity measured against alpha-glucosidase of rat liver ER glucosidase II by colorimetric assay using the D-glucose oxidase-peroxidase method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.46 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501355 | — | — | 1 | 5.08 |
| CHEMBL2442258 | — | — | 1 | 4.30 |
| CHEMBL3084806 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501355 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL2442258 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL3084806 | — | IC50 | = | 100000.0 | nM | 4.00 |