Assay Detail
Binding
CHEMBL648167
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Inhibitory activity measured against alpha-glucosidase of rat liver lysosomal by colorimetric assay using the D-glucose oxidase-peroxidase method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.70 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501355 | — | — | 1 | 6.58 |
| CHEMBL2442258 | — | — | 1 | 6.00 |
| CHEMBL3084806 | — | — | 1 | 5.66 |
| CHEMBL87169 | — | — | 1 | 5.57 |
| CHEMBL2115215 | — | — | 1 | 5.30 |
| CHEMBL2093897 | — | — | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501355 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL2442258 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3084806 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL87169 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL2115215 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL2093897 | — | IC50 | = | 8200.0 | nM | 5.09 |