Glycogen debranching enzyme · SINGLE PROTEIN · Oryctolagus cuniculus
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As of 2026-09-14Protein identity stays anchored to UniProt P35574. Use UniProt P35574 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P35574 as the stable identity anchor, then attach disease evidence before program review.
Glycogen debranching enzyme
Review this target as Glycogen debranching enzyme, mapped to UniProt P35574. Sequence length is 1555 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glycogen debranching enzyme as ChEMBL target CHEMBL5273, mapped to UniProt P35574. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Glycogen debranching enzyme is the right protein anchor across sources, using UniProt P35574 as the stable mapping.
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| Preferred Name | Glycogen debranching enzyme |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | P35574 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glycogen debranching enzyme |
| UniProt Accession | P35574 |
| Component Type | Protein |
| Sequence Length | 1555 aa |
Glycogen debranching enzyme
Review this target as Glycogen debranching enzyme, mapped to UniProt P35574. Sequence length is 1555 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL501355 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL307429 | 6.72 | IC50 | 190.0 | Clinical |
| CHEMBL1561 | 6.41 | IC50 | 390.0 | Approved |
| CHEMBL108084 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL478209 | 5.21 | IC50 | 6100.0 | Preclinical |
| CHEMBL222396 | 4.51 | IC50 | 31000.0 | Preclinical |
| CHEMBL476960 | 4.16 | IC50 | 70000.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 8 | 5.7 |