Assay Detail
Functional
CHEMBL649559
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of antagonist activity towards human Androgen receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.28 | 6.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65743 | — | — | 1 | 6.37 |
| CHEMBL418684 | — | — | 1 | 6.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65743 | — | IC50 | = | 428.0 | nM | 6.37 |
| CHEMBL418684 | — | IC50 | = | 644.0 | nM | 6.19 |