Assay Detail
Binding
CHEMBL649727
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for Alpha adrenergic receptor blocking activity in the isolated rabbit aortic strip preparation; - log KB
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Salicylamide derivatives related to medroxalol with alpha- and beta-adrenergic antagonist and antihypertension activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.08 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1203104 | MEDROXALOL HYDROCHLORIDE | -1.0 | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1203104 | MEDROXALOL HYDROCHLORIDE | Kd | = | 831.76 | nM | 6.08 |