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Assay Detail

CHEMBL649730

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested for inhibition of malt Alpha-amylase by Megazyme assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism malt
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Pancreatic alpha-amylase (CHEMBL2699)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Kinetic characterisation of ene-diol-based inhibitors of alpha-amylase.
Gerrard JA, Prince MJ, Abell AD.
Bioorg Med Chem Lett (2000) 10 : 1575 -1576
PubMed 10915054 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.44 4.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL196 ASCORBIC ACID 4.0 1 4.58
CHEMBL39670 1 4.55
CHEMBL220190 ASCORBYL PALMITATE -1.0 1 4.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL196 ASCORBIC ACID IC50 = 26500.0 nM 4.58
CHEMBL39670 IC50 = 28000.0 nM 4.55
CHEMBL220190 ASCORBYL PALMITATE IC50 = 62500.0 nM 4.20