Assay Detail
Binding
CHEMBL649864
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Binding of [3H]NECA to A2 adenosine receptor (post-Xanthine)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.34 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89939 | — | — | 1 | 7.40 |
| CHEMBL89920 | — | — | 1 | 7.37 |
| CHEMBL91284 | — | — | 1 | 7.29 |
| CHEMBL327708 | — | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89939 | — | Kd | = | 40.0 | nM | 7.40 |
| CHEMBL89920 | — | Kd | = | 43.0 | nM | 7.37 |
| CHEMBL91284 | — | Kd | = | 51.0 | nM | 7.29 |
| CHEMBL327708 | — | Kd | = | 53.0 | nM | 7.28 |