Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL649867

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity for A2 Adenosine receptor in rat striatum using [3H]-CGS- 21680
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Striatum
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Adenosine A2 receptor (CHEMBL2094117)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

2-Alkynyl derivatives of adenosine-5'-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity on platelet aggregation.
Cristalli G, Volpini R, Vittori S, Camaioni E, Monopoli A, Conti A, Dionisotti S, Zocchi C, Ongini E.
J Med Chem (1994) 37 : 1720 -1726
PubMed 8201607 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.91 7.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2113409 1 7.91

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2113409 Ki = 12.4 nM 7.91