Assay Detail
Binding
CHEMBL649990
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Inhibitory activity against TEM-1 Beta-lactamase mutant M182T at 42 degree Centigrade
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
A specific mechanism of nonspecific inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.41 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1160008 | IODOPHTHALEIN | 2.0 | 2 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1160008 | IODOPHTHALEIN | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1160008 | IODOPHTHALEIN | IC50 | = | 5000.0 | nM | 5.30 |