Assay Detail
Functional
CHEMBL650334
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In vitro antiproliferative activity against B16 cell lines
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel cyanoguanidines with potent oral antitumour activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.96 | 8.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL178 | DAUNORUBICIN | 4.0 | 1 | 8.04 |
| CHEMBL17289 | CHS-828 | 1.0 | 1 | 6.55 |
| CHEMBL322225 | — | — | 1 | 6.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL178 | DAUNORUBICIN | IC50 | = | 9.2 | nM | 8.04 |
| CHEMBL17289 | CHS-828 | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL322225 | — | IC50 | = | 530.0 | nM | 6.28 |