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Assay Detail

CHEMBL650502

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Binding
Agonistic activity against C-C chemokine receptor type 3 by displacing [125I]-MCP-4 radioligand, using CCR3 binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

C-C chemokine receptor type 3 (CHEMBL3473)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of potent and selective phenylalanine derived CCR3 antagonists. Part 1.
Dhanak D, Christmann LT, Darcy MG, Jurewicz AJ, Keenan RM, Lee J, Sarau HM, Widdowson KL, White JR.
Bioorg Med Chem Lett (2001) 11 : 1441 -1444
PubMed 11378373 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.15 8.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL33227 1 8.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL33227 IC50 = 7.0 nM 8.15