Assay Detail
Functional
CHEMBL650580
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Protection against C6 glial cell death induced by maitotoxin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | C6 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel dual inhibitors of calpain and lipid peroxidation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.62 | 4.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3706728 | — | — | 1 | 4.81 |
| CHEMBL3706732 | — | — | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3706728 | — | IC50 | = | 15500.0 | nM | 4.81 |
| CHEMBL3706732 | — | IC50 | = | 38500.0 | nM | 4.42 |