Assay Detail
Binding
CHEMBL650826
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]flunitrazepam binding to GABA-A central benzodiazepine receptor of bovine cerebral cortical membranes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
GABA-A receptor; anion channel (CHEMBL2094107) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Bos taurus |
Publication
6,3'-Dinitroflavone, a novel high affinity ligand for the benzodiazepine receptor with potent anxiolytic properties
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.35 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL292868 | — | — | 1 | 7.92 |
| CHEMBL64704 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL292868 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL64704 | — | Ki | = | 17000.0 | nM | 4.77 |