Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL651002

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration required to stimulate pregnenolone formation in the mitochondria of C6-2B glioma cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Subcellular Mitochondria
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis and pharmacological evaluation of benzofuran-acetamides as "antineophobic" mitochondrial DBI receptor complex ligands.
Liao Y, Kozikowski AP, Guidotti A, Costa E.
Bioorg Med Chem Lett (1998) 8 : 2099 -2102
PubMed 9873493 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL63154 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL63154 EC50 = 3.0 nM 8.52