Assay Detail
Functional
CHEMBL651033
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In vitro growth inhibitory effect in human T-cell acute leukemia cells CCRF-CEM
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and characterization of the antitumor activity of novel ceramide analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.12 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL341138 | — | — | 1 | 5.77 |
| CHEMBL128144 | — | — | 1 | 5.10 |
| CHEMBL105867 | — | — | 1 | 4.50 |
| CHEMBL130949 | — | — | 1 | - |
| CHEMBL129124 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL341138 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL128144 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL105867 | — | IC50 | = | 31600.0 | nM | 4.50 |
| CHEMBL130949 | — | IC50 | = | - | nM | - |
| CHEMBL129124 | — | IC50 | = | - | nM | - |