Assay Detail
Functional
CHEMBL651064
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Drug concentration required to inhibit B16 cell growth by 50% after 72 hours of incubation
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Distribution of furamidine analogues in tumor cells: influence of the number of positive charges.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.24 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58173 | — | — | 1 | 5.96 |
| CHEMBL60295 | — | — | 1 | 5.77 |
| CHEMBL61163 | — | — | 1 | 5.64 |
| CHEMBL413767 | — | — | 1 | 5.60 |
| CHEMBL60296 | — | — | 1 | 5.46 |
| CHEMBL60368 | — | — | 1 | 5.07 |
| CHEMBL24057 | FURAMIDINE | -1.0 | 1 | 5.04 |
| CHEMBL62071 | — | — | 1 | 4.37 |
| CHEMBL416502 | — | — | 1 | 4.29 |
| CHEMBL64410 | — | — | 1 | - |
| CHEMBL60339 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58173 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL60295 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL61163 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL413767 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL60296 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL60368 | — | IC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL24057 | FURAMIDINE | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL62071 | — | IC50 | = | 43200.0 | nM | 4.37 |
| CHEMBL416502 | — | IC50 | = | 51400.0 | nM | 4.29 |
| CHEMBL64410 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL60339 | — | IC50 | > | 100000.0 | nM | - |