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Assay Detail

CHEMBL651562

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Functional
Agonist activity against cloned human beta-1 adrenergic receptor as percent activation of adenyl cyclase activity at a concentration of 1000 nM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Beta-1 adrenergic receptor (CHEMBL213)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor.
Weber AE, Mathvink RJ, Perkins L, Hutchins JE, Candelore MR, Tota L, Strader CD, Wyvratt MJ, Fisher MH.
Bioorg Med Chem Lett (1998) 8 : 1101 -1106
PubMed 9871716 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL267306 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL267306 EC50 = 3.0 nM 8.52