Assay Detail
Functional
CHEMBL651571
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for agonist activity against cloned human beta-1 adrenergic receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.25 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267545 | — | — | 1 | 6.47 |
| CHEMBL12450 | — | — | 1 | 6.35 |
| CHEMBL274807 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267545 | — | EC50 | = | 340.0 | nM | 6.47 |
| CHEMBL12450 | — | EC50 | = | 450.0 | nM | 6.35 |
| CHEMBL274807 | — | EC50 | = | 1200.0 | nM | 5.92 |