Assay Detail
Binding
CHEMBL651615
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibitory concentration Beta-2 adrenergic receptor in Guinea pig trachea
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Synthesis and preliminary evaluation of (R,R)(S,S) 5-(2-(2-[4-(2-[(18)F]fluoroethoxy)phenyl]-1-methylethylamino)-1-hydroxyethyl)-benzene-1,3-diol ([(18)F]FEFE) for the in vivo visualisation and quantification of the beta2-adrenergic receptor status in lung.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.22 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92103 | — | — | 1 | 7.22 |
| CHEMBL32800 | FENOTEROL | 4.0 | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92103 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL32800 | FENOTEROL | IC50 | = | 60.0 | nM | 7.22 |