Assay Detail
Binding
CHEMBL651658
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of beta adrenergic receptor on isolated guinea pig atria against isoprenaline at 4E-8M
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Conformational effects on the activity of drugs. 10. Synthesis, conformation, and pharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanols and their morpholine analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.28 | 5.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6995 | PRACTOLOL | 4.0 | 1 | 5.78 |
| CHEMBL88087 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6995 | PRACTOLOL | Kd | = | 1659.59 | nM | 5.78 |
| CHEMBL88087 | — | Kd | = | 16982.44 | nM | 4.77 |