Assay Detail
Functional
CHEMBL651754
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effect of compound against Moloney murine sarcoma virus (MSV)-induced transformation of C3H/3T3 embryo murine fibroblasts
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | C3H/3T3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.63 | 5.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL40302 | — | — | 1 | 5.93 |
| CHEMBL416624 | — | — | 1 | 5.54 |
| CHEMBL289937 | — | — | 1 | 5.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL40302 | — | EC50 | = | 1180.0 | nM | 5.93 |
| CHEMBL416624 | — | EC50 | = | 2860.0 | nM | 5.54 |
| CHEMBL289937 | — | EC50 | = | 3900.0 | nM | 5.41 |