Assay Detail
Binding
CHEMBL652025
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Inhibitory activity against Angiotensin I converting enzyme (ACE) from bovine kidney
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Tissue | Kidney |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Computer-aided selection of potential antihypertensive compounds with dual mechanism of action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.76 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL331575 | — | — | 1 | 9.00 |
| CHEMBL322069 | — | — | 1 | 6.52 |
| CHEMBL326801 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL331575 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL322069 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL326801 | — | IC50 | = | 500000.0 | nM | - |