Assay Detail
Functional
CHEMBL652127
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Compound was evaluated for the blockade of [Pro]SP-induced IPs hydrolysis in CHO cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Asymmetric synthesis of Boc-N-methyl-p-benzoyl-phenylalanine. Preparation of a photoreactive antagonist of substance P.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.15 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2372068 | — | — | 1 | 7.60 |
| CHEMBL2372065 | — | — | 1 | 7.35 |
| CHEMBL2110361 | — | — | 1 | 7.20 |
| CHEMBL2372070 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2372068 | — | Kd | = | 25.12 | nM | 7.60 |
| CHEMBL2372065 | — | Kd | = | 44.67 | nM | 7.35 |
| CHEMBL2110361 | — | Kd | = | 63.1 | nM | 7.20 |
| CHEMBL2372070 | — | Kd | = | 346.74 | nM | 6.46 |