Assay Detail
Functional
CHEMBL652128
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Compound was evaluated for the blockade of [Pro]SP-induced cAMP formation in CHO cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Asymmetric synthesis of Boc-N-methyl-p-benzoyl-phenylalanine. Preparation of a photoreactive antagonist of substance P.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.42 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2110361 | — | — | 1 | 7.80 |
| CHEMBL2372068 | — | — | 1 | 7.74 |
| CHEMBL2372065 | — | — | 1 | 7.19 |
| CHEMBL2372070 | — | — | 1 | 6.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2110361 | — | Kd | = | 15.85 | nM | 7.80 |
| CHEMBL2372068 | — | Kd | = | 18.2 | nM | 7.74 |
| CHEMBL2372065 | — | Kd | = | 64.57 | nM | 7.19 |
| CHEMBL2372070 | — | Kd | = | 114.82 | nM | 6.94 |