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Assay Detail

CHEMBL652171

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The concentration of compound to inhibit Beta-lactamase was measured on Enterobacter cloacae SC 12368
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterobacter cloacae
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Beta-lactamase (CHEMBL2725)
Type SINGLE PROTEIN
Organism Enterobacter cloacae

Publication

Synthesis and biological activity of 7-alkylidenecephems.
Buynak JD, Wu K, Bachmann B, Khasnis D, Hua L, Nguyen HK, Carver CL.
J Med Chem (1995) 38 : 1022 -1034
PubMed 7699694 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1439 TAZOBACTAM SODIUM 4.0 1 5.40
CHEMBL8371 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1439 TAZOBACTAM SODIUM IC50 = 4000.0 nM 5.40
CHEMBL8371 IC50 > 20000.0 nM -