Assay Detail
Binding
CHEMBL652441
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity constant for Benzodiazepine receptor in rat RG-2 glioma cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | RG2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Modulation of melphalan resistance in glioma cells with a peripheral benzodiazepine receptor ligand-melphalan conjugate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.46 | 8.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL286346 | RO-54864 | — | 1 | 8.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL286346 | RO-54864 | Kd | = | 3.5 | nM | 8.46 |