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Assay Detail

CHEMBL652459

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for beta-lactamase inhibition activity of Escherichia cloacae after 15 min of pre-incubation with the enzyme at 37 degree C
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Enterobacter cloacae
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Beta-lactamase (CHEMBL2725)
Type SINGLE PROTEIN
Organism Enterobacter cloacae

Publication

Synthesis and biological activity of novel penem sulfoxides and sulfones
Pfaendler HR, Weishaupt R, Medicus C
Bioorg Med Chem Lett (1997) 7 : 2217 -2222
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL403 SULBACTAM 4.0 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL403 SULBACTAM IC50 = 1000.0 nM 6.00