Assay Detail
Functional
CHEMBL652516
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effect of compound against Moloney murine sarcoma virus (MSV)-induced transformation of C3H/3T3 embryo murine fibroblasts
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | C3H/3T3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
cycloSal-Pronucleotides of 2'-fluoro-ara- and 2'-fluoro-ribo-2',3'- dideoxyadenosine as a strategy to bypass a metabolic blockade.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 5.55 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL295071 | — | — | 1 | 5.77 |
| CHEMBL2112391 | — | — | 1 | 5.55 |
| CHEMBL40874 | — | — | 1 | 5.33 |
| CHEMBL42467 | — | — | 1 | - |
| CHEMBL432291 | — | — | 1 | - |
| CHEMBL42429 | — | — | 1 | - |
| CHEMBL297105 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL295071 | — | EC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL2112391 | — | EC50 | = | 2830.0 | nM | 5.55 |
| CHEMBL40874 | — | EC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL42467 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL432291 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL42429 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL297105 | — | EC50 | > | 50000.0 | nM | - |