Assay Detail
Binding
CHEMBL652670
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Compound was evaluated for its Beta adrenergic receptor blocking action
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.61 | 8.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL266195 | ALPRENOLOL | 2.0 | 1 | 8.64 |
| CHEMBL51667 | — | — | 1 | 8.37 |
| CHEMBL53849 | — | — | 1 | 7.01 |
| CHEMBL53935 | — | — | 1 | 4.60 |
| CHEMBL416300 | — | — | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL266195 | ALPRENOLOL | IC50 | = | 2.3 | nM | 8.64 |
| CHEMBL51667 | — | IC50 | = | 4.3 | nM | 8.37 |
| CHEMBL53849 | — | IC50 | = | 98.0 | nM | 7.01 |
| CHEMBL53935 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL416300 | — | IC50 | = | 38000.0 | nM | 4.42 |