Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL652748

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Alpha-1-adrenergic receptor binding affinity of the compound, value taken from literature
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-1 (CHEMBL1907610)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Synthesis, biological evaluation, and pharmacophore generation of new pyridazinone derivatives with affinity toward alpha(1)- and alpha(2)-adrenoceptors.
Barbaro R, Betti L, Botta M, Corelli F, Giannaccini G, Maccari L, Manetti F, Strappaghetti G, Corsano S.
J Med Chem (2001) 44 : 2118 -2132
PubMed 11405649 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.68 9.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL301707 1 9.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL301707 Ki = 0.21 nM 9.68