Assay Detail
Binding
CHEMBL652855
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Binding affinity for retinoic acid receptor RAR beta
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of retinoic acid receptor-alpha specific amides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 6.25 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 7.96 |
| CHEMBL326911 | — | — | 1 | 6.42 |
| CHEMBL69367 | — | — | 1 | 5.85 |
| CHEMBL106527 | — | — | 1 | 5.83 |
| CHEMBL439780 | — | — | 1 | 5.19 |
| CHEMBL107430 | NRX195183 | 2.0 | 1 | - |
| CHEMBL107054 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | Kd | = | 11.0 | nM | 7.96 |
| CHEMBL326911 | — | Kd | = | 380.0 | nM | 6.42 |
| CHEMBL69367 | — | Kd | = | 1400.0 | nM | 5.85 |
| CHEMBL106527 | — | Kd | = | 1470.0 | nM | 5.83 |
| CHEMBL439780 | — | Kd | = | 6400.0 | nM | 5.19 |
| CHEMBL107430 | NRX195183 | Kd | > | 1000000.0 | nM | - |
| CHEMBL107054 | — | Kd | > | 100000.0 | nM | - |