Assay Detail
Binding
CHEMBL653039
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Displacement of [3H]Ro-5-4864 from rat kidney peripheral benzodiazepine receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.73 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL135870 | — | — | 1 | 8.77 |
| CHEMBL135869 | — | — | 1 | 8.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL135870 | — | IC50 | = | 1.7 | nM | 8.77 |
| CHEMBL135869 | — | IC50 | = | 2.1 | nM | 8.68 |