Assay Detail
Functional
CHEMBL653106
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for cytotoxic activity against CH1/Cs cell line(human ovarian carcinoma)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CH1/Cs |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
N4-(omega-Aminoalkyl)-1-[(omega-aminoalkyl)amino]-4- acridinecarboxamides: novel, potent, cytotoxic, and DNA-binding agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.31 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL342519 | — | — | 1 | 7.00 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.35 |
| CHEMBL141654 | — | — | 1 | 6.28 |
| CHEMBL11359 | CISPLATIN | 4.0 | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL342519 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL141654 | — | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL11359 | CISPLATIN | IC50 | = | 2400.0 | nM | 5.62 |