Assay Detail
Binding
CHEMBL653136
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Equilibrium dissociation constant (KD) against beta adrenergic receptor of rat lung tissue
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Alkylating beta-blockers: activity of isomeric bromoacetyl alprenolol menthanes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.15 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL46136 | BROMOACETYL ALPRENOLOL MENTHANE | — | 2 | 7.70 |
| CHEMBL47370 | — | — | 2 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL46136 | BROMOACETYL ALPRENOLOL MENTHANE | Kd | = | 19.8 | nM | 7.70 |
| CHEMBL46136 | BROMOACETYL ALPRENOLOL MENTHANE | Kd | = | 54.5 | nM | 7.26 |
| CHEMBL47370 | — | Kd | = | 126.0 | nM | 6.90 |
| CHEMBL47370 | — | Kd | = | 188.0 | nM | 6.73 |