Assay Detail
Binding
CHEMBL653138
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Binding affinity against beta adrenergic receptor from rat heart tissues was determined
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Affinity labels for beta-adrenoceptors: preparation and properties of alkylating beta-blockers derived from indole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.14 | 9.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL157881 | — | — | 1 | 9.34 |
| CHEMBL348176 | — | — | 1 | 9.21 |
| CHEMBL156754 | — | — | 1 | 8.74 |
| CHEMBL156628 | — | — | 1 | 7.65 |
| CHEMBL47370 | — | — | 1 | 7.51 |
| CHEMBL46136 | BROMOACETYL ALPRENOLOL MENTHANE | — | 1 | 6.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL157881 | — | Ki | = | 0.46 | nM | 9.34 |
| CHEMBL348176 | — | Ki | = | 0.61 | nM | 9.21 |
| CHEMBL156754 | — | Ki | = | 1.83 | nM | 8.74 |
| CHEMBL156628 | — | Ki | = | 22.6 | nM | 7.65 |
| CHEMBL47370 | — | Ki | = | 31.2 | nM | 7.51 |
| CHEMBL46136 | BROMOACETYL ALPRENOLOL MENTHANE | Ki | = | 391.0 | nM | 6.41 |