Assay Detail
Binding
CHEMBL653139
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Binding affinity against beta adrenergic receptor from rat lung tissues was determined
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Affinity labels for beta-adrenoceptors: preparation and properties of alkylating beta-blockers derived from indole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.20 | 8.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL157881 | — | — | 1 | 8.87 |
| CHEMBL348176 | — | — | 1 | 8.83 |
| CHEMBL156754 | — | — | 1 | 8.56 |
| CHEMBL156628 | — | — | 1 | 8.35 |
| CHEMBL47370 | — | — | 1 | 7.70 |
| CHEMBL46136 | BROMOACETYL ALPRENOLOL MENTHANE | — | 1 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL157881 | — | Ki | = | 1.34 | nM | 8.87 |
| CHEMBL348176 | — | Ki | = | 1.49 | nM | 8.83 |
| CHEMBL156754 | — | Ki | = | 2.78 | nM | 8.56 |
| CHEMBL156628 | — | Ki | = | 4.46 | nM | 8.35 |
| CHEMBL47370 | — | Ki | = | 19.8 | nM | 7.70 |
| CHEMBL46136 | BROMOACETYL ALPRENOLOL MENTHANE | Ki | = | 126.0 | nM | 6.90 |