Assay Detail
Binding
CHEMBL653305
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Compound was tested for Cholesteryl ester transfer protein (CETP) inhibition by CETP-SPA assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Wiedendiol-A and -B, cholesteryl ester transfer protein inhibitors from the marine sponge Xestospongia wiedenmayeri
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.99 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL352031 | CHOLOROPUUPEHENONE | — | 1 | 6.52 |
| CHEMBL160587 | — | — | 1 | 5.30 |
| CHEMBL64152 | — | — | 1 | 5.30 |
| CHEMBL157844 | PUUPEHENONE | — | 1 | 5.22 |
| CHEMBL347038 | — | — | 1 | 4.64 |
| CHEMBL459814 | AVAROL | — | 1 | 4.60 |
| CHEMBL155552 | — | — | 1 | 4.34 |
| CHEMBL155085 | ILIMAQUINONE | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL352031 | CHOLOROPUUPEHENONE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL160587 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL64152 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL157844 | PUUPEHENONE | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL347038 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL459814 | AVAROL | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL155552 | — | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL155085 | ILIMAQUINONE | IC50 | = | 100000.0 | nM | 4.00 |