Assay Detail
Functional
CHEMBL653530
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Effective concentration of compound against HIV-1 LAI strain in CEM-SS cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New bicyclam-GalCer analogue conjugates: synthesis and in vitro anti-HIV activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.11 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | 8.20 |
| CHEMBL18442 | PLERIXAFOR | 4.0 | 1 | 6.90 |
| CHEMBL145521 | — | — | 1 | 6.04 |
| CHEMBL3215409 | — | — | 1 | 5.28 |
| CHEMBL3215411 | — | — | 1 | 5.22 |
| CHEMBL3215412 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | EC50 | = | 6.3 | nM | 8.20 |
| CHEMBL18442 | PLERIXAFOR | EC50 | = | 127.0 | nM | 6.90 |
| CHEMBL145521 | — | EC50 | = | 910.0 | nM | 6.04 |
| CHEMBL3215409 | — | EC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL3215411 | — | EC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL3215412 | — | EC50 | = | 10000.0 | nM | 5.00 |