Assay Detail
Functional
CHEMBL653531
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration against HIV-1RF induced cytopathicity in CEM-SS cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Correlation of anti-HIV potency with lipophilicity in a series of cosalane analogs having normal alkenyl and phosphodiester chains as cholestane replacements.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 4.68 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3138187 | — | — | 1 | 5.52 |
| CHEMBL347774 | — | — | 1 | 4.88 |
| CHEMBL146902 | — | — | 1 | 4.70 |
| CHEMBL149650 | — | — | 1 | 4.37 |
| CHEMBL150234 | — | — | 1 | 4.31 |
| CHEMBL150235 | — | — | 1 | 4.29 |
| CHEMBL116347 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3138187 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL347774 | — | EC50 | = | 13100.0 | nM | 4.88 |
| CHEMBL146902 | — | EC50 | = | 19800.0 | nM | 4.70 |
| CHEMBL149650 | — | EC50 | = | 43200.0 | nM | 4.37 |
| CHEMBL150234 | — | EC50 | = | 49000.0 | nM | 4.31 |
| CHEMBL150235 | — | EC50 | = | 51800.0 | nM | 4.29 |
| CHEMBL116347 | — | EC50 | = | 329000.0 | nM | - |