Assay Detail
Functional
CHEMBL653537
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Effective concentration required to inhibit the replication of HIV-1 in CEMSS human T4 lymphoblastoid cell lines
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Increase of the adenallene anti-HIV activity in cell culture using its bis(tBuSATE) phosphotriester derivative.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.09 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL264014 | — | — | 1 | 5.92 |
| CHEMBL313478 | — | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL264014 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL313478 | — | EC50 | = | 56000.0 | nM | 4.25 |