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Assay Detail

CHEMBL653606

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effective concentration for inhibition of virus production in human CEM cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CCRF-CEM
Confidence 1 — Organism
Curated By Intermediate

Target

CCRF-CEM (CHEMBL382)
Type CELL-LINE
Organism Homo sapiens

Publication

L-beta-(2S,4S)- and L-alpha-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships.
Kim HO, Schinazi RF, Shanmuganathan K, Jeong LS, Beach JW, Nampalli S, Cannon DL, Chu CK.
J Med Chem (1993) 36 : 519 -528
PubMed 8496934 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.05 8.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL300793 1 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL300793 EC50 = 9.0 nM 8.05