Assay Detail
Functional
CHEMBL653875
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Effect on HIV-induced cytopathogenesis in CEM cells.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.49 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL40724 | — | — | 1 | 7.00 |
| CHEMBL853 | ZALCITABINE | 4.0 | 1 | 6.52 |
| CHEMBL2448180 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL40724 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL853 | ZALCITABINE | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL2448180 | — | EC50 | = | 1100.0 | nM | 5.96 |