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Assay Detail

CHEMBL653981

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity of compound was tested against CHO cell line (Chinese hamster ovary) after incubation for 24 hour
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Cell Type CHO
Confidence 1 — Organism
Curated By Intermediate

Target

CHO (CHEMBL613853)
Type CELL-LINE
Organism Cricetulus griseus

Publication

A new designed tumor selective daunomycin derivative
Maligres P, Nicolaou K, Wrasidlo W
Bioorg Med Chem Lett (1993) 3 : 1051 -1054
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.81 6.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1563 DAUNORUBICIN HYDROCHLORIDE 4.0 1 6.41
CHEMBL274803 1 5.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1563 DAUNORUBICIN HYDROCHLORIDE IC50 = 390.0 nM 6.41
CHEMBL274803 IC50 = 6300.0 nM 5.20