Assay Detail
Functional
CHEMBL653984
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Growth inhibitory activity against CHO cells in culture.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5'-[4-(Pivaloyloxy)-1,3,2-dioxaphosphorinan-2-yl]-2'-deoxy-5-fluorouridine: a membrane-permeating prodrug of 5-fluoro-2'-deoxyuridylic acid (FdUMP).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.97 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3143333 | — | — | 1 | 5.30 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 5.30 |
| CHEMBL721 | ACROLEIN | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3143333 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL721 | ACROLEIN | IC50 | = | 50000.0 | nM | 4.30 |