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Assay Detail

CHEMBL653985

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro cytotoxic activity against DNA-double strand break repair deficient Chinese Hamster Ovary (CHO) cell-line EM9
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Cell Type CHO
Confidence 1 — Organism
Curated By Intermediate

Target

CHO (CHEMBL613853)
Type CELL-LINE
Organism Cricetulus griseus

Publication

Structural requirements for biological activity of the marine alkaloid ascididemin
Lindsay BS, Barrows LR, Copp BR
Bioorg Med Chem Lett (1995) 5 : 739 -742
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.75 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL133514 BENZOSAMPANGINE 1 4.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL133514 BENZOSAMPANGINE IC50 = 18000.0 nM 4.75