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Assay Detail

CHEMBL653991

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro cytotoxicity against CHO cells was determined using MTT colorimetric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Cell Type CHO
Confidence 1 — Organism
Curated By Intermediate

Target

CHO (CHEMBL613853)
Type CELL-LINE
Organism Cricetulus griseus

Publication

In vitro antimalarial activity of a series of cationic 2,2'-bipyridyl- and 1,10-phenanthrolineplatinum(II) benzoylthiourea complexes.
Egan TJ, Koch KR, Swan PL, Clarkson C, Van Schalkwyk DA, Smith PJ.
J Med Chem (2004) 47 : 2926 -2934
PubMed 15139771 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.86 6.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL493439 EMETINE HYDROCHLORIDE 2.0 1 6.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL493439 EMETINE HYDROCHLORIDE IC50 = 139.0 nM 6.86