Assay Detail
Binding
CHEMBL654235
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of human serum Butyrylcholinesterase using butyrylthiocholine as substrate; 0.00029-0.001
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and preliminary structure-activity relationships of 1-[(3-fluoro-4-pyridinyl)amino]-3-methyl-1H-indol-5-yl methyl carbamate (P10358), a novel acetylcholinesterase inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.16 | 9.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433041 | EPTASTIGMINE | 2.0 | 1 | 9.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433041 | EPTASTIGMINE | IC50 | = | 0.69 | nM | 9.16 |