Assay Detail
Binding
CHEMBL654291
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Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CV-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
5-Benzylidene 1,2-dihydrochromeno[3,4-f]quinolines, a novel class of nonsteroidal human progesterone receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.06 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137103 | — | — | 1 | 6.43 |
| CHEMBL302362 | — | — | 1 | 5.98 |
| CHEMBL342426 | — | — | 1 | 5.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137103 | — | IC50 | = | 371.0 | nM | 6.43 |
| CHEMBL302362 | — | IC50 | = | 1050.0 | nM | 5.98 |
| CHEMBL342426 | — | IC50 | = | 1650.0 | nM | 5.78 |