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Assay Detail

CHEMBL654368

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effect on HIV-induced cytopathogenesis in CEM cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type CCRF-CEM
Confidence 1 — Organism
Curated By Intermediate

Target

CCRF-CEM (CHEMBL382)
Type CELL-LINE
Organism Homo sapiens

Publication

Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.
Siddiqui MA, Driscoll JS, Marquez VE, Roth JS, Shirasaka T, Mitsuya H, Barchi JJ, Kelley JA.
J Med Chem (1992) 35 : 2195 -2201
PubMed 1351945 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.24 4.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL68878 1 4.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL68878 EC50 = 57700.0 nM 4.24