Assay Detail
Functional
CHEMBL654515
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Cytotoxicity was determined against Chinese hamster ovary mutant cell line(CHO-MG)
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO-MG |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of N1-(anthracen-9-ylmethyl)triamines as molecular recognition elements for the polyamine transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.92 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL539791 | — | — | 1 | 5.47 |
| CHEMBL312821 | — | — | 1 | 5.15 |
| CHEMBL89548 | — | — | 1 | 5.11 |
| CHEMBL544313 | — | — | 1 | 5.06 |
| CHEMBL543610 | — | — | 1 | 5.02 |
| CHEMBL554675 | — | — | 1 | 5.00 |
| CHEMBL419683 | — | — | 1 | 4.97 |
| CHEMBL422775 | — | — | 1 | 4.96 |
| CHEMBL92204 | — | — | 1 | 4.95 |
| CHEMBL545253 | — | — | 1 | 4.24 |
| CHEMBL540552 | — | — | 1 | 4.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL539791 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL312821 | — | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL89548 | — | IC50 | = | 7800.0 | nM | 5.11 |
| CHEMBL544313 | — | IC50 | = | 8800.0 | nM | 5.06 |
| CHEMBL543610 | — | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL554675 | — | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL419683 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL422775 | — | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL92204 | — | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL545253 | — | IC50 | = | 57300.0 | nM | 4.24 |
| CHEMBL540552 | — | IC50 | = | 66700.0 | nM | 4.18 |